Formulation and evaluation of tramadol hydrochloride rectal suppositories
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چکیده
منابع مشابه
Formulation and Evaluation of Tramadol hydrochloride Rectal Suppositories
Rectal suppositories of tramadol hydrochloride were prepared using different bases and polymers like PEG, cocoa butter, agar and the effect of different additives on in vitro release of tramadol hydrochloride was studied. The agar-based suppositories were non-disintegrating/non-dissolving, whereas PEGs were disintegrating/dissolving and cocoa butter were melting suppositories. All the prepared ...
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Chloral hydrate (CH) is a short-term sedative and hypnotic normally given to children as a syrup to assist with sleep and alleviate anxiety prior to painful dental or medical procedures which entail the patient to be still (e.g. scans and EEGs) [1, 2]. However, when given orally, it exhibits a bitter taste and the most common adverse reaction shown is gastric irritation. Moreover, the onset of ...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2008
ISSN: 0250-474X
DOI: 10.4103/0250-474x.45405